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KMID : 0380020040190040284
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Korean Journal of Biotechnology and Bioengineering
2004 Volume.19 No. 4 p.284 ~ p.287
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Extraction of Acanthoside-D from Acanthopanax Cortex using Supercritical Carbon Dioxide
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Yang Si-Joong
Shin Jae-Soon
Kang Choon-Hyoung
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Abstract
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The purpose of this study was to find an optimum extraction condition of acanthoside-D from acanthopanax cortex with supercritical carbon dioxide as a solvent. In this effort, effects of the extraction conditions including pressure, temperature and presence or absence of a cosolvent on the extraction efficiency were investigated. The ethanol, water or 50% methanol was used as a cosolvent whilst the operating pressure ranged from 200 bar to 300 bar. The acanthoside-D concentrations were determined by means of HPLC equipped with a UV detector. From the results, it was observed that increase of higher pressure led to the higher extraction efficiency. Further, water was found to be the best cosolvent among the entrainers tested.
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KEYWORD
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Acanthoside-D, acanthopanax cortex, supercritical fluid extraction, cosolvent
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